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What is Circadian Misalignment?

What is Circadian Misalignment?
Our internal rhythms can become out of sync with one another and with the cycles of our environment. Let’s find out more about circadian misalignment and how this might affect us.

Circadian rhythms are patterns in physiology and behaviour which run on a cycle of around 24 hours, driven by an internal clock. The demands of our hectic modern society can cause our internal rhythms to become out of sync with our environmental cycles as well as becoming misaligned with one another. The term ‘circadian misalignment’ applies to a whole range of circumstances, one of which is when our sleep/wake cycle becomes out of sync with the day and night cues of our environment. With holiday season under way, a relevant example of this is jet lag… so let’s find out more.

Jet lag and circadian misalignment

Jet lag occurs when our sleep/wake cycle is in sync with the time zone of our original location and is therefore misaligned with the day and night cycle of our destination. Symptoms of jet lag include difficulties falling asleep at night and staying awake during the day, issues with concentration and even digestive problems.

One method of reducing the symptoms of jet lag is to try to adjust your internal clock towards the destination time zone before travelling and light therapy can be a powerful tool! There is no one-size-fits-all method for achieving this, and the schedule that you follow will be dependent on multiple factors including your current sleep/wake schedule and the sleep/wake schedule that you intend to have whilst in the new time zone, the number of time zones which will be crossed during your flight and the number of days available to try to adapt. See guidance on adjusting your sleep/wake cycle ahead of travel here.

Lumie Vitamin L helps to regulate the sleep/wake cycle

We have all heard of jet lag, but what about social jet lag?

Social jet lag

Social jet lag occurs when our internal rhythms become out of sync with cycles of our society, often due to social commitments such as work. Due to habitual misalignment of their internal rhythms and actual sleep/wake times, shift workers experience social jet lag which causes symptoms similar to that of jet lag due to long haul travelling. It is suggested that as well as the circadian rhythms of shift workers being out of sync with the light/dark cycle of their environment, the circadian disruption caused by their working schedules may also cause various levels of the internal circadian system to become out of sync with one another. Because of this, shift work has been associated with various health issues including metabolic health, heart health, mental health and cancer.

Light as a cue for circadian rhythms

Light is the most powerful synchroniser of our circadian rhythms, and when they become out of sync, light therapy can be an effective tool for regulating them. Bright light therapy works by mimicking natural daylight, stimulating the brain and suppressing the production of melatonin, the hormone which is conducive to sleep. When sleep and waking does not align with the light cues of the environment, for example in the case of shift workers, bright light therapy can help to regulate the internal rhythm. A daily session of bright light therapy upon waking can help to boost mood, energy and alertness, leaving you feeling refreshed.

Dawn simulation also helps you to feel ready for sleep and to wake much more gently than with a regular alarm. Lumie wake-up lights offer an effective solution for unwinding at bedtime, whatever time that may be, and waking gradually, whether that is in the morning or in the middle of the night. The sunrise and sunset features of these lights stimulate appropriate hormones through light. Fading light is a natural cue for the body to increase the production of the sleep hormone, melatonin, allowing you to wind down and feel ready for sleep. When it is time to wake up, the sunrise feature of Lumie wake-up lights activates with gradually increasing levels of light, prompting the suppression of melatonin production and allowing you to wake feeling rejuvenated.

Feel bright upon waking with Lumie Bodyclock 700FM

So, whether you're preparing for a long haul flight or are looking to make your sleep and waking a little easier, Lumie light therapy lamps are a trusted companion!

Further reading on circadian misalignment

Banks, Siobhan, et al. "Circadian misalignment and metabolic consequences: shiftwork and altered meal times." Modulation of sleep by obesity, Diabetes, age, and diet (2015): 155-164.

Baron, Kelly Glazer, and Kathryn J Reid. “Circadian misalignment and health.” International review of psychiatry (Abingdon, England) vol. 26,2 (2014): 139-54. doi:10.3109/09540261.2014.911149

Boivin, Diane B., Philippe Boudreau, and Anastasi Kosmadopoulos. "Disturbance of the circadian system in shift work and its health impact." Journal of biological rhythms 37.1 (2022): 3-28.

Caliandro, Rocco, et al. "Social jetlag and related risks for human health: a timely review." Nutrients 13.12 (2021): 4543.

Hulsegge, Gerben, et al. "Shift work, sleep disturbances and social jetlag in healthcare workers." Journal of Sleep Research 28.4 (2019): e12802.

Inokawa, Hitoshi, et al. "Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice." Scientific reports 10.1 (2020): 2569.

James, Stephen M., et al. "Shift work: disrupted circadian rhythms and sleep—implications for health and well-being." Current sleep medicine reports 3 (2017): 104-112.

Scheer, Frank AJL, et al. "Adverse metabolic and cardiovascular consequences of circadian misalignment." Proceedings of the National Academy of Sciences 106.11 (2009): 4453-4458.

Wong, Patricia M., et al. "Social jetlag, chronotype, and cardiometabolic risk." The Journal of Clinical Endocrinology & Metabolism 100.12 (2015): 4612-4620.